Author(s) Details:
Gangaram Bhadarge
Department of Biochemistry, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Sawangi (Meghe), Wardha-442001, India.
Nandkishor Bankar
Datta Meghe Medical College, Nagpur, Datta Meghe Institute of Higher Education and Research, India.
Sudhir Singh
Datta Meghe Medical College, Nagpur, Datta Meghe Institute of Higher Education and Research, India.
This section is a part of the chapter: Serum Zinc and Vitamin A Levels in Tuberculosis Patients: A Comprehensive Study
Malnutrition is a condition in which a deficiency of one or many nutrients has an adverse effect on cells, tissues, organs, and the body understood as a whole, which is manifested in the deterioration of its functioning and a negative change in the overall clinical picture. It is a major public health problem in all developing countries. Malnutrition is strongly implicated in the development and progression of tuberculosis. Tuberculosis (TB) is a leading infectious cause of death worldwide, despite ongoing efforts to limit its incidence and mortality. The presence of malnutrition may worsen TB. Preventing and treating all forms of malnutrition is an important tool to limit the spread of TB worldwide and improve TB outcomes and treatment efficacy. Increasing the incidence and severity of infection and TB is a prime example Malnutrition as shown by low body mass index (BMI) is common in TB patients and increases mortality due to TB. In addition to macronutrient deficiency, micronutrient availability has been found to be an important factor in TB outcomes. Other dietary symptoms, such as middle upper arm circumference (MUAC) and weight gain, are also associated with malnutrition. Zinc and vitamin A are two important micronutrients. The role of zinc and vitamin A deficiency in cell defense, an effective way to prevent tuberculosis, was found in this controlled study. While micronutrients such as zinc and vitamin A can affect the functioning of the body, the extent to which these micro-factors affect the outcome of TB remains unknown. The effects of zinc and vitamin A on the immune system have led to the question of whether this low chemical deficiency is associated with an increased risk of serious tuberculosis. However, proving this theory is difficult as the acute phase response in inflammation causes depletion of plasma zinc and vitamin A in the form of plasma retinol.
How to Cite
Bhadarge, G. ., Bankar, N. ., & Singh, S. . (2025). Serum Zinc and Vitamin A Levels in Tuberculosis Patients: A Comprehensive Study. Pharmaceutical Science: New Insights and Developments Vol. 4, 39–45. https://doi.org/10.9734/bpi/psnid/v4/4715